Thursday, October 08, 2015

INTRACELLULAR STRUCTURES OF PROKARYOTES

Hello everyone! Today, I would like to share with you guys about the components that can be found inside the cells. Do you have any idea on what they have inside their cute little body?

First, the intracellular structures include plasma membrane, cytoplasm, nuclear area, ribosomes, inclusions and endospores.

We have learnt this for several times in high school, matriculation and previous semester. They function as a selectively permaeble barrier, systhesizes cell wall components, assists in DNA replication, carries on respiration and captures energy as ATP. The process that includes the plasma membrane are the passive transport (osmosis, simple diffusion and facilitated diffusion) and active transport.


Cytoplasm consists of 80% water. It also contains protein, carbohydrates, lipids, inorganic ions and many low molecular weight compounds. The major structures in the prokaryotic cytoplasm are DNA, ribosomes and inclusions. Prokaryotic cytoplasm lacks of cytoskeleton.

The nuclear area is a single long circular molecule of double-stranded DNA. Bacterial chromosomes do not include histones and are not surrounded by nuclear envelope. Bacteria often contain small circular, double-stranded DNA molecules called plasmid.


Ribosomes function as the sites of protein synthesis, they can be inhibited by certain antibiotics. Cells that have high rates of protein synthesis, have a large number of ribosomes in their cells!


Streptomycin and gentamicin can attach to the 30S subunit to inhibit the protein synthesis.

Types of inclusions are :

  • Granules → metachromatic granules, polysaccharide granules and sulfur granules
  • Vesicles → gas vacuoles, carboxysomes, magnetosomes and lipid deposits

Some inclusions are common to a wide variety of bacteria, whereas others are limited to a small number of species and therefore serve as a basis for identification.

Endospores cannot be destroyed easily even by harsh chemicals. They are formed internal to the bacterial cell membrane. Endospores formation leads to a highly dehydrated structure thick walls and additional layers. They contain essential macromolecules and a variety of substances absent from vegetative cells.


Bacteria that can cause disease because of their endospores are :
  • Bacillus anthracis
  • Clostridium tetani
  • Clostridium botulinum
  • Clostridium perfringens
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Dr. Sieo Chin Chin.. I still remember the first day I met you at the foyer of Biotech 1 because of our Thank-A-Microbe Exhibition. You are one of the judges! :') We explained to you about our microbe, this.. and that.. We also wrongly wrote the bacteria name and you correct it. You are so kind and cheerful!

That moment when you teach us about immunology, it was incredibly fun! You are sooooooooooooooooooooo knowledgeable. You even teach us until out of the topic hahaha. But it is really good to know all that, seriously! Very interesting! About culture collection bank, the process and so on.

Dr. Sieo NEVER getting mad in her class even when she didn't get any response from us when she asked questions. Still remember Bacillus choyii? :') Hahaha. Dr gave that name from our coursemate, Choy. I will never forget each part of what you have taught us, Dr Sieo..

Honestly, I feel like I'm starting to miss you. Thank you so much for teaching us, Dr. Your kind of quiz that we had last semester really awesome! We had so much fun! 

When I open my edmodo account, I saw your picture. When I open my whatsapp contacts, I saw your profile picture :'(


You will never be forgotten. May you rest in peace, Dr. Sieo Chin Chin.